Sepsis is something we’ve all heard about, there have been some high profile cases in the media, generally highlighting cases where sepsis has been mistaken for something else and proven fatal.
The statistics… 5 people die in the UK every hour, due to sepsis and 40% of survivors are left with permanent, life changing after effects. Those are some pretty shocking statistics right?
So, what is sepsis and why is it so important to recognise the signs and symptoms early on?
Sepsis (aka blood poisoning) is simply the immune system’s overreaction to an infection or injury.
Normally our immune system fights infection – but sometimes, for reasons we don’t yet fully understand, it attacks our body’s own organs and tissues. If it’s not treated immediately, sepsis can result in tissue damage, organ failure and even death. But, if it’s diagnosed early, it can be treated with antibiotics.
One of the difficulties is that sepsis can basically jump on the back of many other common infections, such as UTIs and chest infections. Symptoms vary massively, can appear very similar to flu or gastroenteritis in the early stages, and are different for adults and children.
Ambulance crews generally have a low tolerance for sepsis and use guidance from The Sepsis Trust and their own Trust protocols to help make decisions. This means that you might hear the terms ‘Red Flag’ or ‘Amber Flag for sepsis’ bandied about. It doesn’t mean that a patient always has sepsis, just that the symptoms present are acting as an early warning and there’s potential for sepsis to develop.
Crews who identify the potential will then follow a protocol which is aimed to start treatment early and improve the chance of a good recovery.
How does sepsis start?
Sepsis can start anywhere in your body and may be only in one part, or it can be widespread. Your immune system usually works to fight any germs, such as bacteria, viruses or fungi and to prevent infection. But sepsis can result from this ‘over reaction’ to any infection including:
- a chest infection causing pneumonia
- a urine infection in the bladder
- a problem in the abdomen, such as a burst ulcer or a hole in the bowel
- an infected cut or bite
- a wound from trauma or surgery
- a leg ulcer or cellulitis
- Sepsis can be caused by a huge variety of different germs, like streptococcus, e-coli, MRSA or C diff. Most cases are actually caused by common bacteria, which wouldn’t normally make us too ill.
- The symptoms:
- Feeling like you have a bad case of flu, gastroenteritis or a chest infection.
- Fever, chills, shivering.
- A fast heart rate. (Pulse Oximiter, manual pulse)
- Increased breathing rate. (Count the resp rate)
- Dizziness.
- Feeling faint.
- Confusion or disorientation.
- Nausea and vomiting.
- Diarrhoea.
- Cold and clammy.
- Cold extremities.
- Pale or mottled skin.
- Low oxygen saturation levels. (Pulse oximeter)
- Low blood pressure. (BP monitor)
- Low temperature * (Tympanic thermometer)
- *While a high temperature is a good indication of infection somewhere, sepsis can cause the temperature to drop. Also remember that people can be shivery (rigors) if they’re too hot as well as too cold.
Of course many of these symptoms apply to a multitude of other common medical conditions and it’s only as they develop that sepsis can be distinguished.
It’s still not known why some people who get an infection develop sepsis and others don’t. But we do know that people are more likely to develop sepsis after a viral illness like a cold, or a minor injury. Sepsis can affect anyone, regardless of age or state of health. However some individuals are more vulnerable, particularly if they’re very young or old, are diabetic, are having chemotherapy, have recently had surgery or given birth or have any conditions which affect their immune system.
There’s a really useful FAQ section on the Sepsis Trust website which you can access here:
Of course, in our maritime environment, the important factor is to make sure we are equipped to recognise the symptoms early and get in touch with your Telemedicine support at the first opportunity.
Our advice is to be suspicious! All infections have the potential to develop into sepsis. Monitor and carry out regular checks of vital signs on anyone who is feeling unwell.
This short checklist using the SEPSIS mnemonic for adults might be useful.
1. Patients with sepsis normally look very unwell. The NEWS2 score isn’t covered on STCW courses so don’t worry about that.
2. Consider the source of infection. Remember that if they have a temperature it normally indicates an infection somewhere, even if you don’t know where.
3. You can’t measure lactate or exact urine output. But all of the other points can be measured onboard and you can ask about urine output or monitor whether the patient is passing any urine. Even if they haven’t had a pee for a few hours, that’s not normal and could be a warning sign.
4. Most of these points can also be assessed onboard.
Treatment options onboard will be limited, so that ‘be suspicious’ is really important because someone with sepsis needs to be in a hospital.
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